Genetic characterization and emergence of the metallo-β-lactamase GIM-1 in Pseudomonas spp. and Enterobacteriaceae during a long-term outbreak.

نویسندگان

  • Andreas F Wendel
  • Alexander H B Brodner
  • Stephan Wydra
  • Sofija Ressina
  • Birgit Henrich
  • Klaus Pfeffer
  • Mark A Toleman
  • Colin R Mackenzie
چکیده

Since the first isolation in 2002, the metallo-β-lactamase GIM-1 has not been detected outside Germany. The data presented here, for 50 clinical blaGIM-1-positive isolates, including Pseudomonas spp. and Enterobacteriaceae (Enterobacter cloacae, Klebsiella oxytoca, Serratia marcescens, Escherichia coli, and Citrobacter freundii), collected between 2007 and 2012 at the original site in an ongoing outbreak, demonstrate a diverse genetic background and dissemination of the gene conferring resistance to enteric bacteria.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 57 10  شماره 

صفحات  -

تاریخ انتشار 2013